Ketamine-Assisted Therapy
Rapid relief for treatment-resistant depression, PTSD, and anxiety.
Legal (off-label)
See if Ketamine fits. Free assessmentKetamine-assisted therapy is one of the most evidence-supported treatments available for people with treatment-resistant depression, PTSD, and chronic anxiety. Unlike traditional antidepressants, which can take weeks to produce results and frequently fail in treatment-resistant cases, ketamine works rapidly, often within hours of the first session.
Ketamine is administered nationwide by licensed medical providers in clinical settings. Spravato (esketamine), the nasal-spray form, is FDA-approved for treatment-resistant depression. IV and intramuscular ketamine are used off-label for depression and other indications. A standard initial course typically involves around six sessions over two to three weeks, and many patients experience meaningful relief within the first one to three sessions.
Navii connects patients with vetted ketamine clinics and KAP therapists who combine ketamine administration with psychotherapeutic support for deeper and more lasting outcomes.
Who it's for
People who have not responded to antidepressants, those seeking rapid relief from severe depression or suicidal ideation, PTSD patients, and people open to emerging psychiatric approaches.
Common questions
Is ketamine therapy legal in the United States?+
Yes. Ketamine is legally administered nationwide by licensed medical providers. Spravato (esketamine) is FDA-approved for treatment-resistant depression; IV and IM ketamine are used off-label for depression in clinical settings.
How fast does ketamine work for depression?+
Many patients experience meaningful relief within hours to days of the first session, with deeper results emerging over a course of around six sessions across two to three weeks.
Does insurance cover ketamine therapy?+
Coverage varies. Spravato (esketamine) is covered by many plans for treatment-resistant depression. IV/IM ketamine is often out-of-pocket. Your Navii navigator can help you understand coverage at vetted clinics.
Other treatments
Psilocybin
Guided psilocybin sessions in legal Oregon and Colorado service centers.
MDMA
Structured therapeutic support for complex PTSD and trauma.
TMS
FDA-cleared, non-invasive treatment for depression, OCD, and anxious depression.
IOP / PHP
Structured, multi-day-per-week care without a residential stay.
Residential
24/7 structured care in an immersive therapeutic environment.
Trauma intensive
Multi-day deep-dive trauma work with a specialist therapist.